That person is so rude.

那个人太粗鲁了。

How rude can you be?

你简直太粗鲁了。

That really makes me mad/angry/upset.

那简直要让我发疯/生气/烦透了。

He drives me crazy when he does that. 

他那样做简直让我发疯。

She is the most unpleasant woman I've ever met. 

她是我见过的最令人讨厌的女人。

I'm mad/angry/upset about what you said.

你的话让我很气愤/生气/烦。

Because of you, I'm in a bad mood. 

都是因为你，让我心情很糟糕。

That makes me feel bad/unhappy/upset. 

那让我感觉很糟糕/不高兴/生气。

Things like that are what really burn me.

那种事情总是让我发火。

Things like that really drive me crazy. 

那种事情总让我心烦。

I'm feeling a little bitter about what happened. 

对于所发生的事情，我感到有些失望。

I'm not happy about what you did. 

你的所作所为让我不高兴。

Those kinds of situations put me in a bad mood. 

这种状况让我的心情非常糟糕。

Conversation:

A: What's wrong? You don't look too happy.

B: No, I'm not.

A: Why? What happened?

B: I was talking with a customer who came into the office today. He was going to ABC University and he made a remark about DEF University which I went to. That really put me in a bad mood.

A: Try not to let it get to you. Why don't you sit down here? I'll give you a massage.

Notes:

1.What's wrong?还可以说：What's wrong with you?或What's the matter(with you)?

2.You don't look too happy.还可以说：You look unhappy/upset.

3.get to sb表示“影响到某人”

Translation:

怎么了？你看起来不太高兴。

是啊，我很生气。

为什么？出了什么事？

我今天接待了一位来我们办公室的客户。他要去ABC大学，但对我上的DEF大学评论了一番，让我很不高兴。

别让这件事影响你干脆在这儿坐一坐吧，我来给你做做按摩。